Volume 27, Number 1, January/February 1999Importance de la lipophilie en modélisation moléculaire
|Page(s)||97 - 100|
Determination of phosphorous oxoanions in pharmaceuticals using non-suppressed ion chromatographyM.A. Bello and A.G. González
Department of Analytical Chemistry, Faculty of Chemistry, 41012 Seville, Spain
The separation and quantitation of phosphorous oxoanions have been investigated by non-suppressed ion chromatography (IC) with conductometric detection using a modified gluconate-borate buffer as eluent. Hypophosphite being coeluted with the injection peak, its previous oxidation into phosphate is necessary. The method was applied to the determination of hypophosphite and phosphate in several pharmaceuticals.
Key words: Phosphate determination / hypophosphite determination / pharmaceuticals / non-suppressed Cromatography / conductometric detection.
© EDP Sciences, Wiley-VCH 1999