Free Access
| Issue |
Analusis
Volume 26, Number 3, April 1998
Analyse des corps gras
|
|
|---|---|---|
| Page(s) | 150 - 153 | |
| Section | Original articles | |
| DOI | https://doi.org/10.1051/analusis:1998126 | |
Analusis 26, 150-153 (1998)
DOI: 10.1051/analusis:1998126
Laboratory of Industrial Pharmacy, School of Pharmacy, 1 rue Gaston Veil, 44035 Nantes Cedex, France
Key words: Neohesperidin dihydrochalcone / thermodegradation / aqueous solutions / pH.
© EDP Sciences, Wiley-VCH 1998
DOI: 10.1051/analusis:1998126
Effect of pH on neohesperidin dihydrochalcone thermostability in aqueous solutions
C. Coiffard, L. Coiffard, F. Peigné and Y. De Roeck-HoltzhauerLaboratory of Industrial Pharmacy, School of Pharmacy, 1 rue Gaston Veil, 44035 Nantes Cedex, France
Abstract
The objective of this work was the evaluation of neohesperidin dihydrochalcone thermostability. For this accelerated stability study, we have used an isothermal method at three temperatures (50,
70 and 90 °C). The thermodegradation of aqueous diluted solutions of neohesperidin dihydrochalcone at various pH was studied. This degradation appeared to follow first-order kinetics and was found to be pH-dependent. In the best stability conditions (pH = 4.50), the experiments revealed an activation energy (
) of 45.8 kJ mol-1 and a 
of 164 days, at 20 °C.
Key words: Neohesperidin dihydrochalcone / thermodegradation / aqueous solutions / pH.
© EDP Sciences, Wiley-VCH 1998