Free Access
Issue
Analusis
Volume 26, Number 3, April 1998
Analyse des corps gras
Page(s) 150 - 153
Section Original articles
DOI https://doi.org/10.1051/analusis:1998126
Analusis 26, 150-153 (1998)
DOI: 10.1051/analusis:1998126

Effect of pH on neohesperidin dihydrochalcone thermostability in aqueous solutions

C. Coiffard, L. Coiffard, F. Peigné and Y. De Roeck-Holtzhauer

Laboratory of Industrial Pharmacy, School of Pharmacy, 1 rue Gaston Veil, 44035 Nantes Cedex, France


Abstract
The objective of this work was the evaluation of neohesperidin dihydrochalcone thermostability. For this accelerated stability study, we have used an isothermal method at three temperatures (50, 70 and 90 °C). The thermodegradation of aqueous diluted solutions of neohesperidin dihydrochalcone at various pH was studied. This degradation appeared to follow first-order kinetics and was found to be pH-dependent. In the best stability conditions (pH = 4.50), the experiments revealed an activation energy ($E_{\rm a}$) of 45.8 kJ mol-1 and a $t_{90\%}$ of 164 days, at 20 °C.


Key words: Neohesperidin dihydrochalcone / thermodegradation / aqueous solutions / pH.


© EDP Sciences, Wiley-VCH 1998

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