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Analusis 28, 859-863 (2000)
DOI: 10.1051/analusis:2000157
On the use of a peak deconvolution procedure for the determination of energy barrier to enantiomerization in dynamic chromatography
J. Krupcík1, P. Oswald1, I. Spánik1, P. Májek1, M. Bajdichová1, P. Sandra2 and D.W. Armstrong31 Department of Analytical Chemistry, Faculty of Chemical Technology, Slovak Technical University, Radlinského 9, 812 37 Bratislava, Slovak Republic
2 Laboratory of Organic Chemistry, University of Gent, Krijgslaan 281 (S4), 9000 Gent, Belgium
3 Department of Chemistry, University of Missouri-Rolla, Rolla, Missouri, USA
(Received September 19, 2000; accepted October 5, 2000.)
Abstract
Manual or computer assisted peak deconvolution on chromatograms of
the racemate of 1-chloro-2,2-dimethylaziridine enantiomers GC was
used to determine the peak areas of enantiomers in the racemate prior
(AA,0, AB,0) and after the separation (AA, AB). These peak areas were
used in the determination of apparent rate constants and apparent energy
barrier to enantiomerization. Comparison of apparent energy barriers determined
using deconvolution of chromatograms with data published in literature showed
differences within 7% rel.
Key words: Gas chromatography -- peak deconvolution -- energy barrier to enantiomerization -- 1-chloro-2,2-dimethylaziridine enantiomers.
© EDP Sciences, Wiley-VCH 2000